| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 29th, 2010 | 27 | Yes |
Popular Name: 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-ynylamino)quinazolin-2-one 1-isopropyl-4-(4-isopropylphenyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.17 | 9.96 | -15.95 | 1 | 4 | 0 | 47 | 359.473 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 30 | 0.39 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 30 | 0.39 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events |
