| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 29th, 2010 | 29 | Yes |
Popular Name: 1-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-5-(trifluoromethoxy)indoline-2,3-dione 1-[[4-(1-methylpyrazol-4-yl)phen…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.61 | 8.96 | -15.78 | 0 | 6 | 0 | 66 | 401.344 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ACM5-1-E | Muscarinic Acetylcholine Receptor M5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 3300 | 0.26 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ACM5_HUMAN | P08912 | Muscarinic Acetylcholine Receptor M5, Human | 3300 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Muscarinic acetylcholine receptors |
