| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 31st, 2010 | 26 | Yes |
Popular Name: (2S)-1-[[1,1-dimethyl-2-(1-naphthyl)ethyl]amino]-3-phenoxy-propan-2-ol (2S)-1-[[1,1-dimethyl-2-(1-napht…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.91 | 8.83 | -48.4 | 3 | 3 | 1 | 46 | 350.482 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 210 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 210 | 0.36 | Binding ≤ 1μM |
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 210 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events |
