| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 1st, 2006 | 35 | Yes |
Popular Name: 5-trans Fluprostenol isopropyl ester 5-trans Fluprostenol isopropyl e…
Find On: PubMed — Wikipedia — Google
CAS Number: 1563176-59-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.21 | 7.86 | -12.19 | 3 | 6 | 0 | 96 | 500.554 | 14 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | WO2000018316A2; WO2000054810A1 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PF2R-1-E | Prostaglandin F2-alpha Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 52 | 0.29 | Binding ≤ 10μM |
| PF2R-1-E | Prostaglandin F2-alpha Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Functional ≤ 10μM |
| Z80530-2-O | Swiss-3T3 (Fibroblast Cells) (cluster #2 Of 2), Other | Other | 3 | 0.34 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PF2R_BOVIN | P37289 | Prostanoid FP Receptor, Bovin | 52 | 0.29 | Binding ≤ 1μM |
| PF2R_BOVIN | P37289 | Prostanoid FP Receptor, Bovin | 52 | 0.29 | Binding ≤ 10μM |
| PF2R_HUMAN | P43088 | Prostanoid FP Receptor, Human | 2.7 | 0.34 | Functional ≤ 10μM |
| Z80530 | Z80530 | Swiss-3T3 (Fibroblast Cells) | 2.7 | 0.34 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Prostanoid ligand receptors |
