| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 1st, 2006 | 11 | Yes |
Popular Name: 1,2,3,4-Tetrahydronaphthalen-2-amine 1,2,3,4-Tetrahydronaphthalen-2-a…
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CAS Numbers: 1743-01-7 , 21880-87-5 , 21966-60-9 , 2954-50-9 , 617700-25-1 , [1743-01-7]
(R)-1,2,3,4-Tetrahydro-2-naphthylamine
(R)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine
(R)-1,2,3,4-Tetrahydronaphthalen-2-amine
(S)-1,2,3,4-Tetrahydronaphthalen-2-amine
1,2,3,4-tetrahydro-2-naphthalenamine
1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride
1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE
1,2,3,4-Tetrahydro-naphthalen-2-ylamine
1,2,3,4-Tetrahydro-naphthalen-2-ylamine hydrochloride
1,2,3,4-Tetrahydro-naphthalen-2-ylamine, HCl
1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINEHYDROCHLORIDE
1,2,3,4-tetrahydronaphthalen-2-amine hydrobromide
1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
1,2,3,4-tetrahydronaphthalen-2-ylamine hydrobromide
1,2,3,4-Tetrahydronaphthalen-2-ylamine hydrochloride
2-Amino-1,2,3,4-tetrahydronaphthalene HCl
2-Amino-1,2,3,4-tetrahydronaphthalene hydrochloride
2-Amino-1,2,3,4-tetrahydronaphthalenehydrochloride
2-naphthalenamine, 1,2,3,4-tetrahydro-, hydrobromide
2-Naphthalenamine, 1,2,3,4-tetrahydro-, hydrochloride
2-Naphthalenamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1)
2-Naphthalenamine,1,2,3,4-tetrahydro-, hydrochloride (1:1)
2-Naphthylamine, tetrahydro-, hydrochloride; LS-95832; Tetrahydro-2-naphthylamine hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.49 | 4.22 | -46.12 | 3 | 1 | 1 | 28 | 148.229 | 0 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95% | Fluorochem |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT1A-1-E | Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1B-1-E | Serotonin 1b (5-HT1b) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1D-1-E | Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1E-1-E | Serotonin 1e (5-HT1e) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1F-1-E | Serotonin 1f (5-HT1f) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 380 | 0.82 | Binding ≤ 10μM |
| PNMT-1-E | Phenylethanolamine N-methyltransferase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 6800 | 0.66 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT1A_RAT | P19327 | Serotonin 1a (5-HT1a) Receptor, Rat | 380 | 0.82 | Binding ≤ 1μM |
| 5HT1B_RAT | P28564 | Serotonin 1b (5-HT1b) Receptor, Rat | 380 | 0.82 | Binding ≤ 1μM |
| 5HT1D_RAT | P28565 | Serotonin 1d (5-HT1d) Receptor, Rat | 380 | 0.82 | Binding ≤ 1μM |
| 5HT1E_HUMAN | P28566 | Serotonin 1e (5-HT1e) Receptor, Human | 380 | 0.82 | Binding ≤ 1μM |
| 5HT1F_RAT | P30940 | Serotonin 1f (5-HT1f) Receptor, Rat | 380 | 0.82 | Binding ≤ 1μM |
| PNMT_BOVIN | P10938 | Phenylethanolamine N-methyltransferase, Bovin | 10000 | 0.64 | Binding ≤ 10μM |
| 5HT1A_RAT | P19327 | Serotonin 1a (5-HT1a) Receptor, Rat | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1B_RAT | P28564 | Serotonin 1b (5-HT1b) Receptor, Rat | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1D_RAT | P28565 | Serotonin 1d (5-HT1d) Receptor, Rat | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1E_HUMAN | P28566 | Serotonin 1e (5-HT1e) Receptor, Human | 380 | 0.82 | Binding ≤ 10μM |
| 5HT1F_RAT | P30940 | Serotonin 1f (5-HT1f) Receptor, Rat | 380 | 0.82 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Serotonin receptors |
