| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 7th, 2006 | 19 | Yes |
Popular Name: DNC012535 DNC012535
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.09 | 2.42 | -38.61 | 1 | 2 | 1 | 13 | 256.369 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERG7-1-E | Lanosterol Synthase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2500 | 0.41 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERG7_HUMAN | P48449 | Lanosterol Synthase, Human | 280 | 0.48 | Binding ≤ 1μM |
| ERG7_RAT | P48450 | Lanosterol Synthase, Rat | 2500 | 0.41 | Binding ≤ 10μM |
| ERG7_HUMAN | P48449 | Lanosterol Synthase, Human | 280 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of gene expression by SREBF (SREBP) | |
| Cholesterol biosynthesis |
