| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 11th, 2006 | 27 | Yes |
Popular Name: N-[1-(2-carbamoylpyrrolidin-1-yl)carbonyl-2-phenyl-ethyl]-5-oxo-pyrrolidine-2-carboxamide N-[1-(2-carbamoylpyrrolidin-1-yl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.26 | -6.55 | -21.78 | 4 | 8 | 0 | 121 | 372.425 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRFR-1-E | Thyrotropin-releasing Hormone Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1500 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRFR_MOUSE | P21761 | Thyrotropin-releasing Hormone Receptor, Mouse | 110 | 0.36 | Binding ≤ 1μM |
| TRFR_MOUSE | P21761 | Thyrotropin-releasing Hormone Receptor, Mouse | 110 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
