| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 23rd, 2010 | 29 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.05 | -1.83 | -252.8 | 4 | 15 | -3 | 241 | 470.273 | 7 | ↓ |
| Mid Mid (pH 6-8) | -1.05 | -2.98 | -132.11 | 5 | 15 | -2 | 238 | 471.281 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| P2RY1-1-E | Purinergic Receptor P2Y1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10 | 0.39 | Binding ≤ 10μM |
| P2RY1-1-E | P2Y Purinoceptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 738 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| P2RY1_HUMAN | P47900 | Purinergic Receptor P2Y1, Human | 1.27 | 0.43 | Binding ≤ 1μM |
| P2RY1_HUMAN | P47900 | Purinergic Receptor P2Y1, Human | 1.27 | 0.43 | Binding ≤ 10μM |
| P2RY1_HUMAN | P47900 | Purinergic Receptor P2Y1, Human | 1.88 | 0.42 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| ADP signalling through P2Y purinoceptor 1 | |
| G alpha (q) signalling events | |
| P2Y receptors |
