| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 24th, 2010 | 25 | Yes |
Popular Name: N-(2-chlorophenyl)-6-phenyl-imidazo[1,2-a]pyridine-3-carboxamide N-(2-chlorophenyl)-6-phenyl-imid…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.81 | 11.09 | -9.76 | 1 | 4 | 0 | 46 | 347.805 | 3 | ↓ |
| Lo Low (pH 4.5-6) | 4.81 | 11.58 | -36.7 | 2 | 4 | 1 | 48 | 348.813 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EPHB3-1-E | Ephrin Type-B Receptor 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 60 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EPHB3_HUMAN | P54753 | Ephrin Type-B Receptor 3, Human | 60 | 0.40 | Binding ≤ 1μM |
| EPHB3_HUMAN | P54753 | Ephrin Type-B Receptor 3, Human | 60 | 0.40 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| EPH-ephrin mediated repulsion of cells | |
| EPH-Ephrin signaling | |
| EPHB-mediated forward signaling | |
| Ephrin signaling |
