| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 11th, 2010 | 26 | Yes |
Popular Name: 8-(1-ethylpyrazole-4-carbonyl)-2-(2-methylthiazol-4-yl)-1,3,8-triazaspiro[4.5]dec-1-en-4-one 8-(1-ethylpyrazole-4-carbonyl)-2…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.18 | 2.9 | -18.47 | 1 | 8 | 0 | 92 | 372.454 | 3 | ↓ |
| Hi High (pH 8-9.5) | -1.18 | 2.02 | -50.54 | 0 | 8 | -1 | 95 | 371.446 | 3 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![1,3,8-triazaspiro[4.5]dec-2-en-4-one](http://zinc12.docking.org/img/rings/373583.gif)
![8-(1H-pyrazole-4-carbonyl)-2-thiazol-4-yl-1,3,8-triazaspiro[4.5]dec-2-en-4-one](http://zinc12.docking.org/img/rings/398749.gif)