Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.92	11.86	-40.52	1	5	1	43	409.55	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.92	9.66	-6.31	0	5	0	42	408.542	8	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD-1-E	Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	240	0.31	Binding ≤ 10μM
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	3600	0.25	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD_HUMAN	P41143	Delta Opioid Receptor, Human	240	0.31	Binding ≤ 1μM
OPRD_HUMAN	P41143	Delta Opioid Receptor, Human	240	0.31	Binding ≤ 10μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	3600	0.25	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Homo sapiens (OPRD_HUMAN) Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT) Homo sapiens (OPRD_HUMAN)

No pre-computed analogs available. Try a structural similarity search.