| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 8th, 2011 | 40 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.25 | 8.31 | -51.39 | 8 | 10 | 1 | 162 | 545.664 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLMN-2-E | Plasminogen (cluster #2 Of 2), Eukaryotic | Eukaryotes | 25 | 0.27 | Binding ≤ 10μM |
| TRY1-3-E | Trypsin I (cluster #3 Of 5), Eukaryotic | Eukaryotes | 25 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLMN_RAT | Q01177 | Plasminogen, Rat | 25 | 0.27 | Binding ≤ 1μM |
| TRY1_HUMAN | P07477 | Trypsin I, Human | 25 | 0.27 | Binding ≤ 1μM |
| PLMN_RAT | Q01177 | Plasminogen, Rat | 25 | 0.27 | Binding ≤ 10μM |
| TRY1_HUMAN | P07477 | Trypsin I, Human | 25 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | |
| Degradation of the extracellular matrix | |
| Dissolution of Fibrin Clot | |
| Platelet degranulation | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l | |
| Signaling by PDGF |
