Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	6.87	-54.68	4	5	1	77	420.402	7	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	2.92	6.67	-21.26	3	5	0	75	419.394	7	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
DPP2-2-E	Dipeptidyl Peptidase II (cluster #2 Of 2), Eukaryotic	Eukaryotes	6500	0.25	Binding ≤ 10μM
DPP4-1-E	Dipeptidyl Peptidase IV (cluster #1 Of 3), Eukaryotic	Eukaryotes	1	0.43	Binding ≤ 10μM
DPP8-1-E	Dipeptidyl Peptidase VIII (cluster #1 Of 2), Eukaryotic	Eukaryotes	9900	0.24	Binding ≤ 10μM
DPP9-1-E	Dipeptidyl Peptidase IX (cluster #1 Of 2), Eukaryotic	Eukaryotes	4400	0.26	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DPP4_HUMAN	P27487	Dipeptidyl Peptidase IV, Human	1.3	0.43	Binding ≤ 1μM
DPP2_HUMAN	Q9UHL4	Dipeptidyl Peptidase II, Human	6500	0.25	Binding ≤ 10μM
DPP4_HUMAN	P27487	Dipeptidyl Peptidase IV, Human	1.3	0.43	Binding ≤ 10μM
DPP9_HUMAN	Q86TI2	Dipeptidyl Peptidase IX, Human	4400	0.26	Binding ≤ 10μM
DPP8_HUMAN	Q6V1X1	Dipeptidyl Peptidase VIII, Human	9900	0.24	Binding ≤ 10μM

Description	Species
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Homo sapiens (DPP4_HUMAN)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polyp	Homo sapiens (DPP4_HUMAN)