| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 13th, 2006 | 11 | Yes |
Popular Name: DNC010937 DNC010937
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.62 | -10.88 | -32.12 | 6 | 5 | 1 | 97 | 164.181 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AGAL-1-E | Alpha-galactosidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 780 | 0.78 | Binding ≤ 10μM |
| GLCM-2-E | Glucosylceramidase (cluster #2 Of 2), Eukaryotic | Eukaryotes | 200 | 0.85 | Binding ≤ 10μM |
| LPH-1-E | Lactase-glycosylceramidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7200 | 0.65 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AGAL_COFAR | Q42656 | Alpha-galactosidase, Cofar | 780 | 0.78 | Binding ≤ 1μM |
| AGAL_HUMAN | P06280 | Alpha-galactosidase A, Human | 500 | 0.80 | Binding ≤ 1μM |
| GLCM_HUMAN | P04062 | Beta-glucocerebrosidase, Human | 200 | 0.85 | Binding ≤ 1μM |
| AGAL_COFAR | Q42656 | Alpha-galactosidase, Cofar | 780 | 0.78 | Binding ≤ 10μM |
| AGAL_HUMAN | P06280 | Alpha-galactosidase A, Human | 500 | 0.80 | Binding ≤ 10μM |
| GLCM_HUMAN | P04062 | Beta-glucocerebrosidase, Human | 200 | 0.85 | Binding ≤ 10μM |
| LPH_RAT | Q02401 | Lactase-glycosylceramidase, Rat | 7200 | 0.65 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glycosphingolipid metabolism |
