| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 17th, 2006 | 36 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.93 | -2.68 | -18.53 | 1 | 9 | 0 | 104 | 494.592 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OXYR-1-E | Oxytocin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.33 | Binding ≤ 10μM |
| V2R-1-E | Vasopressin V2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 950 | 0.23 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 180 | 0.26 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OXYR_HUMAN | P30559 | Oxytocin Receptor, Human | 0.65 | 0.36 | Binding ≤ 1μM |
| V2R_HUMAN | P30518 | Vasopressin V2 Receptor, Human | 950 | 0.23 | Binding ≤ 1μM |
| OXYR_HUMAN | P30559 | Oxytocin Receptor, Human | 0.65 | 0.36 | Binding ≤ 10μM |
| V2R_HUMAN | P30518 | Vasopressin V2 Receptor, Human | 950 | 0.23 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 180 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Vasopressin regulates renal water homeostasis via Aquaporins | |
| Vasopressin-like receptors |
