| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 10th, 2011 | 24 | Yes |
Popular Name: (6S)-4-[4-(3,3,3-trifluoropropyl)pyrimidin-2-yl]-1,8-dioxa-4,11-diazaspiro[5.6]dodecane (6S)-4-[4-(3,3,3-trifluoropropyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.77 | 8.06 | -44.14 | 2 | 6 | 1 | 64 | 347.361 | 4 | ↓ |
| Mid Mid (pH 6-8) | 1.77 | 6.67 | -6.66 | 1 | 6 | 0 | 60 | 346.353 | 4 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![1,8-dioxa-4,11-diazaspiro[5.6]dodecane](http://zinc12.docking.org/img/rings/28938.gif)
![4-(2-pyrimidyl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecane](http://zinc12.docking.org/img/rings/29020.gif)