| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 14th, 2006 | 24 | Yes |
Popular Name: N-methyl-N-[[4-[(2-phenyltriazol-4-yl)methylaminomethyl]phenyl]methyl]methanamine N-methyl-N-[[4-[(2-phenyltriazol…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.13 | 1.41 | -93.66 | 3 | 5 | 2 | 51 | 323.444 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERG7-1-E | Lanosterol Synthase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1410 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERG7_HUMAN | P48449 | Lanosterol Synthase, Human | 1410 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of gene expression by SREBF (SREBP) | |
| Cholesterol biosynthesis |
