| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 14th, 2005 | 23 | Yes |
Popular Name: 9-(dimethylamino)-3-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one 9-(dimethylamino)-3-phenylpyrido…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.52 | 9.79 | -39.6 | 1 | 5 | 1 | 52 | 323.401 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM1-1-E | Metabotropic Glutamate Receptor 1 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 20 | 0.47 | Binding ≤ 10μM |
| GRM1-1-E | Metabotropic Glutamate Receptor 1 (cluster #1 Of 5), Eukaryotic | Eukaryotes | 20 | 0.47 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM1_RAT | P23385 | Metabotropic Glutamate Receptor 1, Rat | 19.9986187 | 0.47 | Binding ≤ 1μM |
| GRM1_RAT | P23385 | Metabotropic Glutamate Receptor 1, Rat | 19.9986187 | 0.47 | Binding ≤ 10μM |
| GRM1_HUMAN | Q13255 | Metabotropic Glutamate Receptor 1, Human | 20 | 0.47 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (q) signalling events |
