| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 28th, 2006 | 12 | No |
Popular Name: Norcantharidin Norcantharidin
Find On: PubMed — Wikipedia — Google
CAS Numbers: 29745-04-8 , [29745-04-8]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.88 | 3.01 | -7.11 | 0 | 4 | 0 | 53 | 168.148 | 0 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PP1G-1-E | Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1980 | 0.67 | Binding ≤ 10μM |
| Q8AWE3-1-E | Serine-threonine Protein Phosphatase 2A Regulatory Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 370 | 0.75 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Q8AWE3_CHICK | Q8AWE3 | Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick | 370 | 0.75 | Binding ≤ 1μM |
| Q8AWE3_CHICK | Q8AWE3 | Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick | 370 | 0.75 | Binding ≤ 10μM |
| PP1G_HUMAN | P36873 | Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit, Human | 1980 | 0.67 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Downregulation of TGF-beta receptor signaling | |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |
| Mitotic Prometaphase | |
| Resolution of Sister Chromatid Cohesion | |
| Separation of Sister Chromatids |
