UCSF

Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit, Human (18 Compounds)

Swissprot:
PP1G_HUMAN
Stitch:
PP1G_HUMAN
UniProt:
P36873
ChEMBL:
CHEMBL4438
Reactome:
REACT_120727
REACT_494
REACT_682
REACT_150425
REACT_150471
PDB:
1IT6 (DOCK)
1JK7 (DOCK)
1U32 (DOCK)
2BCD (DOCK)
2BDX (DOCK)
PPP1CC

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 18 4 1 1
Binding ≤ 1μM 5 3 1 1
Uniprot Swissprot Chembl Description Number Shared
PP1A_HUMAN P62136 CHEMBL2164 Serine/threonine Protein Phosphatase PP1-alpha Catalytic Subunit, Human 8

Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis

Uniprot Swissprot Chembl Description Number Shared
PP1A_HUMAN P62136 CHEMBL2164 Serine/threonine Protein Phosphatase PP1-alpha Catalytic Subunit, Human 8

Mitotic Prometaphase

Uniprot Swissprot Chembl Description Number Shared
2A5A_HUMAN Q15172 CHEMBL4763 Serine/threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Alpha Isoform, Human 1
PP2AA_HUMAN P67775 CHEMBL4703 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Human 1
PP2AB_HUMAN P62714 CHEMBL2435 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Beta Isoform, Human 2

Resolution of Sister Chromatid Cohesion

Uniprot Swissprot Chembl Description Number Shared
2A5A_HUMAN Q15172 CHEMBL4763 Serine/threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Alpha Isoform, Human 1
PP2AA_HUMAN P67775 CHEMBL4703 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Human 1
PP2AB_HUMAN P62714 CHEMBL2435 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Beta Isoform, Human 2

Separation of Sister Chromatids

Uniprot Swissprot Chembl Description Number Shared
2A5A_HUMAN Q15172 CHEMBL4763 Serine/threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Alpha Isoform, Human 1
PP2AA_HUMAN P67775 CHEMBL4703 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Human 1
PP2AB_HUMAN P62714 CHEMBL2435 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Beta Isoform, Human 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PP1G-1-E Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit (cluster #1 Of 2), Eukaryotic 15 4 1 1
PP1G-2-E Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit (cluster #2 Of 2), Eukaryotic 3 0 0 0
Uniprot Swissprot Chembl Description Number Shared
Q8AWE3_CHICK Q8AWE3 CHEMBL2669 Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick 12
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 10
PP1A_HUMAN P62136 CHEMBL2164 Serine/threonine Protein Phosphatase PP1-alpha Catalytic Subunit, Human 8
PPM1B_HUMAN O75688 CHEMBL2845 Protein Phosphatase 2C Beta, Human 7
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 2
MPIP2_HUMAN P30305 CHEMBL4804 Dual Specificity Phosphatase Cdc25B, Human 2
PP2AB_HUMAN P62714 CHEMBL2435 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Beta Isoform, Human 2
PTPRC_HUMAN P08575 CHEMBL3243 Leukocyte Common Antigen, Human 2
YOPH_YEREN P15273 CHEMBL4404 Tyrosine-protein Phosphatase YopH, Yeren 2
2A5A_HUMAN Q15172 CHEMBL4763 Serine/threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Alpha Isoform, Human 1
2AAA_MOUSE Q76MZ3 CHEMBL3557 Serine/threonine Protein Phosphatase 2A, 65 KDa Regulatory Subunit A, Alpha Isoform, Mouse 1
2ABG_HUMAN Q9Y2T4 CHEMBL2507 Serine/threonine Protein Phosphatase 2A, 55 KDa Regulatory Subunit B, Gamma Isoform, Human 1
DUS3_HUMAN P51452 CHEMBL2635 Dual Specificity Protein Phosphatase 3, Human 1
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 1
PP2AA_BOVIN P67774 CHEMBL3862 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Bovin 1
PP2AA_HUMAN P67775 CHEMBL4703 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Human 1
PP2AA_MOUSE P63330 CHEMBL2451 Serine/threonine Protein Phosphatase 2A, Catalytic Subunit, Alpha Isoform, Mouse 1
PPAC_HUMAN P24666 CHEMBL4903 Low Molecular Weight Phosphotyrosine Protein Phosphatase, Human 1
PPM1J_MOUSE Q149T7 CHEMBL2776 Protein Phosphatase 2A Catalytic Subunit Zeta, Mouse 1
PTN2_HUMAN P17706 CHEMBL3807 T-cell Protein-tyrosine Phosphatase, Human 1
PTPA_HUMAN Q15257 CHEMBL2505 Protein Phosphatase 2A Regulatory Subunit B', Human 1
PTPRF_HUMAN P10586 CHEMBL3521 Receptor-type Tyrosine-protein Phosphatase F (LAR), Human 1