UCSF

T-cell Protein-tyrosine Phosphatase, Human (430 Compounds)

Swissprot:
PTN2_HUMAN
Stitch:
PTN2_HUMAN
UniProt:
P17706
ChEMBL:
CHEMBL3807
PDB:
1L8K (DOCK)
PTPN2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 430 8 4 7
Binding ≤ 1μM 277 1 0 6

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PTN11_HUMAN Q06124 CHEMBL3864 Protein-tyrosine Phosphatase 2C, Human 45 6 4 2
PTN12_HUMAN Q05209 CHEMBL3236 Protein-tyrosine Phosphatase G1, Human 2 0 0 0
PTN13_HUMAN Q12923 CHEMBL2976 Protein-tyrosine Phosphatase 1E, Human 5 1 0 0
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 1,512 31 25 26
PTN22_HUMAN Q9Y2R2 CHEMBL2889 Hematopoietic Cell Protein-tyrosine Phosphatase 70Z-PEP, Human 60 10 0 0
PTN6_HUMAN P29350 CHEMBL3166 Protein-tyrosine Phosphatase 1C, Human 27 0 0 0
PTN7_HUMAN P35236 CHEMBL2219 Protein-tyrosine Phosphatase LC-PTP, Human 49 4 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
PTN2-1-E T-cell Protein-tyrosine Phosphatase (cluster #1 Of 3), Eukaryotic 326 4 0 4
PTN2-2-E T-cell Protein-tyrosine Phosphatase (cluster #2 Of 3), Eukaryotic 72 4 4 0
PTN2-3-E T-cell Protein-tyrosine Phosphatase (cluster #3 Of 3), Eukaryotic 35 0 0 3
Uniprot Swissprot Chembl Description Number Shared
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 425
PTPRF_HUMAN P10586 CHEMBL3521 Receptor-type Tyrosine-protein Phosphatase F (LAR), Human 56
MPIP2_HUMAN P30305 CHEMBL4804 Dual Specificity Phosphatase Cdc25B, Human 23
PTN6_HUMAN P29350 CHEMBL3166 Protein-tyrosine Phosphatase 1C, Human 14
PTPRA_HUMAN P18433 CHEMBL3918 Receptor-type Tyrosine-protein Phosphatase Alpha, Human 7
PTPRC_HUMAN P08575 CHEMBL3243 Leukocyte Common Antigen, Human 6
PPAC_HUMAN P24666 CHEMBL4903 Low Molecular Weight Phosphotyrosine Protein Phosphatase, Human 3
PTPRB_HUMAN P23467 CHEMBL2706 Receptor-type Tyrosine-protein Phosphatase Beta, Human 3
Q7ARH8_YERPE Q7ARH8 CHEMBL3643 Secreted Protein-tyrosine Phosphatase, Yerpe 3
DPOLB_RAT P06766 CHEMBL4343 DNA Polymerase Beta, Rat 2
PTN11_HUMAN Q06124 CHEMBL3864 Protein-tyrosine Phosphatase 2C, Human 2
PYGM_RABIT P00489 CHEMBL4696 Glycogen Phosphorylase, Muscle Form, Rabit 2
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 1
DPOLB_HUMAN P06746 CHEMBL2392 DNA Polymerase Beta, Human 1
DUS3_HUMAN P51452 CHEMBL2635 Dual Specificity Protein Phosphatase 3, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
PA21B_NAJME P00599 CHEMBL3967 Phospholipase A2 Isozyme DE-I, Najme 1
PA2A_PROFL P59264 CHEMBL5022 Phospholipase A2 Isozyme PLA-A, Profl 1
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 1
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 1
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 1
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 1
PP1A_HUMAN P62136 CHEMBL2164 Serine/threonine Protein Phosphatase PP1-alpha Catalytic Subunit, Human 1
PP1G_HUMAN P36873 CHEMBL4438 Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit, Human 1
PTP1_YEAST P25044 CHEMBL4452 Protein-tyrosine Phosphatase 1, Yeast 1
Q7T3S7_ECHCA Q7T3S7 CHEMBL4195 Phospholipase A2, Echca 1

Most Common Rings