| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 4th, 2006 | 23 | No |
Popular Name: 1,3-diethyl-6-hydroxy-5-(indol-3-ylidenemethyl)-2-thioxo-pyrimidin-4-one 1,3-diethyl-6-hydroxy-5-(indol-3…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.67 | 9.42 | -10.28 | 1 | 5 | 0 | 60 | 327.409 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TNR1A-1-E | Tumor Necrosis Factor Receptor R1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TNR1A_HUMAN | P19438 | Tumor Necrosis Factor Receptor R1, Human | 1000 | 0.37 | Binding ≤ 1μM |
| TNR1A_HUMAN | P19438 | Tumor Necrosis Factor Receptor R1, Human | 1000 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| TNF signaling |
