UCSF

Tumor Necrosis Factor Receptor R1, Human (30 Compounds)

Swissprot:
TNR1A_HUMAN
Stitch:
TNR1A_HUMAN
UniProt:
P19438
ChEMBL:
CHEMBL3378
Reactome:
REACT_1432
PDB:
1EXT (DOCK)
1FT4 (DOCK)
1ICH (DOCK)
1NCF (DOCK)
1TNR (DOCK)
TNFRSF1A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 30 6 0 0
Binding ≤ 1μM 18 3 0 0
Functional ≤ 10μM 62 5 1 1

Reactome Network (1)

Reactome ID Description Species
REACT_1432 TNF signaling Homo sapiens

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 2
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 2
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z80356 Z80356 CHEMBL614214 OVCAR-5 (Ovarian Adenocarcinoma Cells) 1
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 1
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 1