UCSF

ZINC08214681

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 4th, 2006 40 No

Popular Name: Streptomycin Streptomycin

Find On: PubMed — Wikipedia — Google

CAS Numbers: 3810-74-0 , 57-92-1

Other Names:

mycin

2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside; SM; [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-

3810-74-0; D01350; Streptomycin sulfate (JP16/USP); Streptomycin sulfate (TN)

57-92-1; C00413; Streptomycin

57-92-1; D08531; SM; Streptomycin (INN); Streptomycin (TN)

57-92-1; streptomycin

Agrept

Agrimycin

AI3-50158; AS-15; Agri-Strep; Agrimycin 17; Agristrep; Ambistryn S; Bis-(4-O-(2-O-(2-desoxy-2-methylamino-alpha-L-glucopyranosyl)-alpha-L-streptosyl)-L-streptidin)-trisulfat; C21H39N7O12.H2O4S; CCRIS 5934; Caswell No. 804A; D-Streptamine, O-2-deoxy-2-(met

Ambistrin; Dihydrostreptomycin and streptomycin; Duo-streptomycin; LS-16546; Streptomycin and dihydrostreptomycin

CHEBI:45745; CHEBI:9284; CHEBI:15119; CHEBI:26784

EINECS 228-182-9; LS-147062; Streptomycin hydrochloride; Streptomycin, trihydrochloride

EINECS 228-328-1; LS-101247; Pantothenic acid, D-, compd. with streptomycin (1:1); S-Pantothenat [German]; SM-Pantothenat [German]; Streptomycin-pantothenate; Streptothenate; d-Streptamine, O-2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl-(1.2)-O-5-deoxy-

Estreptomicina

INN); Streptomycin Sulfate (FDA

JAN

Kantrex

LS-187084

LS-189975

Merstep

Streptomisin

Streptomycin (BAN

Streptomycin (sulfate)

Streptomycin a Sulfate

Streptomycin a Sulfate;Streptomycin Sesquisulfate Hydrate;Streptomycin Sesquisulphate Hydrate;Streptomycin Sulfate;Streptomycin Sulphate;Streptomycin, Sulfate Salt

Streptomycin Sesquisulfate Hydrate

Streptomycin Sesquisulfate Hydrate;Streptomycin a Sulfate;Streptomycin Sulfate;Streptomycin Sulphate;Streptomycin, Sulfate Salt;Streptomycin Sesquisulphate Hydrate

Streptomycin Sulfate

Streptomycin Sulphate

streptomycin(3+)

Streptomycin, Sulfate Salt

streptomycin; streptomycin trication

USP)

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -5.28 -14.78 -150.46 19 19 3 339 584.604 11 ↓
Mid Mid (pH 6-8) -5.28 -16.18 -95.14 18 19 2 335 583.596 11 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 1.28e+01 g/l DrugBank-approved
mechanism Activity increased in alkaline medium binds irreversibly to the bacterial ribosomal 30S subunit IBScreen Bioactives
UniProt Database Links AFRP_STRGR; AFSA_STRGR; APHE_STRGR; GLSA_STRGR; ICAR_STAEQ; MCA_MYCS2; MFS55_MYCBO; NORM_VIBCH; NORM_VIBPA; OBG_STRGR; RMLA_STRGR; RMLB_STRGR; RMLC_STRGR; RMLD_STRGR; RR12_SOLNI; RR5_SPIOL; RS12_BACSU; RS12_BARHE; RS12_ECOLI; RS12_HAEIN; RS12_LEPBP; RS12_ ChEBI
biological_use Aminoglycoside antibiotic IBScreen Bioactives IBScreen Bioactives
mechanism Apoptosis-inducer IBScreen Bioactives
mechanism Blocks the recognition step in protein-synthesis IBScreen Bioactives
mechanism Causes misreading of the genetic code IBScreen Bioactives
mechanism Causes ribosomal dissociation from messenger RNA IBScreen Bioactives
biological_use Clinically used broad spectrum antibacterial (tuberculostatic) agent IBScreen Bioactives
PUBCHEM_PATENT_ID EP0520843A2; EP0520843A3; EP0716690A1; EP1017800A1; EP1020529A3; EP1029062A1; US4777136; US4918163; US5100791; US5482856; US5484591; US5541095; US5629198; US5698198; US5912266; US5932483; US5977076; US6004948; US6146883; WO1993009838A1; WO1995006716A1; WO IBM Patent Data
Patent Database Links EP1452533; EP1522307; EP1588702; EP1598059; EP1607406; EP1700845; EP1803463; EP1815856; EP1908754; EP1956079; EP1972684; GB1585736; GB2103617; US2003105066; US2004198669; US2005065197; US2006222684; US2007185040; US2007202051; US2007202077; US2007207222 ChEBI
mechanism Protein synthesis inhibitor IBScreen Bioactives IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )