| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 21st, 2005 | 22 | No |
Popular Name: 1-(4-chlorophenyl)-2-(3-ethyl-2-imino-benzoimidazol-1-yl)-ethanone 1-(4-chlorophenyl)-2-(3-ethyl-2-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.17 | 12.7 | -33.75 | 2 | 4 | 1 | 52 | 314.796 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CXCR3-1-E | C-X-C Chemokine Receptor Type 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 700 | 0.39 | Binding ≤ 10μM |
| CXCR3-1-E | C-X-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3500 | 0.35 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CXCR3_HUMAN | P49682 | C-X-C Chemokine Receptor Type 3, Human | 700 | 0.39 | Binding ≤ 1μM |
| CXCR3_HUMAN | P49682 | C-X-C Chemokine Receptor Type 3, Human | 700 | 0.39 | Binding ≤ 10μM |
| CXCR3_HUMAN | P49682 | C-X-C Chemokine Receptor Type 3, Human | 3500 | 0.35 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
