In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
May 14th, 2007 | 17 | Yes |
Popular Name: 2-phenylquinolin-4-ol 2-phenylquinolin-4-ol
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1144-20-3 , 14802-18-7 , [1144-20-3]
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.55 | 7.85 | -13.63 | 1 | 2 | 0 | 33 | 221.259 | 1 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TBA1A-2-E | Tubulin Alpha-3 Chain (cluster #2 Of 3), Eukaryotic | Eukaryotes | 7300 | 0.42 | Binding ≤ 10μM |
TBB1-1-E | Tubulin Beta-1 Chain (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7300 | 0.42 | Functional ≤ 10μM |
TBB3-3-E | Tubulin Beta-3 Chain (cluster #3 Of 3), Eukaryotic | Eukaryotes | 7300 | 0.42 | Functional ≤ 10μM |
TBB4A-3-E | Tubulin Beta-4 Chain (cluster #3 Of 3), Eukaryotic | Eukaryotes | 7300 | 0.42 | Functional ≤ 10μM |
TBB4B-3-E | Tubulin Beta-2 Chain (cluster #3 Of 3), Eukaryotic | Eukaryotes | 7300 | 0.42 | Functional ≤ 10μM |
TBB8-3-E | Tubulin Beta-8 Chain (cluster #3 Of 3), Eukaryotic | Eukaryotes | 7300 | 0.42 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TBA1A_PIG | P02550 | Tubulin Alpha Chain, Pig | 7300 | 0.42 | Binding ≤ 10μM |
TBB1_HUMAN | Q9H4B7 | Tubulin Beta-1 Chain, Human | 7300 | 0.42 | Functional ≤ 10μM |
TBB4B_HUMAN | P68371 | Tubulin Beta-2 Chain, Human | 7300 | 0.42 | Functional ≤ 10μM |
TBB3_HUMAN | Q13509 | Tubulin Beta-3 Chain, Human | 7300 | 0.42 | Functional ≤ 10μM |
TBB4A_HUMAN | P04350 | Tubulin Beta-4 Chain, Human | 7300 | 0.42 | Functional ≤ 10μM |
TBB8_HUMAN | Q3ZCM7 | Tubulin Beta-8 Chain, Human | 7300 | 0.42 | Functional ≤ 10μM |
Description | Species |
---|---|
Formation of tubulin folding intermediates by CCT/TriC | |
Gap junction assembly | |
Kinesins | |
Loss of Nlp from mitotic centrosomes | |
Loss of proteins required for interphase microtubule organization from the ce | |
MHC class II antigen presentation | |
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | |
Mitotic Prometaphase | |
Post-chaperonin tubulin folding pathway | |
Prefoldin mediated transfer of substrate to CCT/TriC | |
Recruitment of mitotic centrosome proteins and complexes | |
Recruitment of NuMA to mitotic centrosomes | |
Recycling pathway of L1 | |
Regulation of PLK1 Activity at G2/M Transition | |
Resolution of Sister Chromatid Cohesion | |
Separation of Sister Chromatids | |
Translocation of GLUT4 to the plasma membrane |