| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 3rd, 2005 | 16 | Yes |
Popular Name: 5-Hydroxy-L-tryptophan 5-Hydroxy-L-tryptophan
Find On: PubMed — Wikipedia — Google
CAS Numbers: 114-03-4 , 145224-90-4 , 17469-40-8 , 314062-44-7 , 4350-07-6 , 4350-09-8 , 56-69-9 , 9/8/4350 12:00:00 AM , [114-03-4] , [17469-40-8] , [4350-09-8] , [56-69-9]
(2S)-2-ammonio-3-(5-hydroxy-1H-indol-3-yl)propanoate; 5-hydroxy-L-tryptophan
(R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacid
(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)-propionic acid
(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid hydrate
(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid hydrochloride
2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
4350-09-8; D07339; Levothym (TN); Oxitriptan (INN)
5-HTP; 5-Hydroxytryptophan; 56-69-9; C01017
5-HYDROXY-L-TRYPTOPHAN HYDRATE
5-hydroxy-L-tryptophan zwitterion
5-Hydroxy-L-Tryptophan [4350-09-8]; ((-)5-Hydroxy-L-tryptophan)
5-HYDROXY-L-TRYPTOPHAN; [4350-09-8]
5-Hydroxy-L-Tryptophan;Hydroxy-5 L-tryptophane
5-hydroxytryptophan L-form; Cincofarm; L-5-hydroxytryptophan; Levothym; Tript-OH; oxitriptan
CHEBI:2064; CHEBI:20577; CHEBI:12133
D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
DL-2-Amino-3-(5-hydroxyindolyl)propionic acid
DL-2-Amino-3-[3-(5-hydroxyindole)]propionic acid
L-2-Amino-3-(5-hydroxyindolyl)-propionic acid hydrochloride
L-2-Amino-3-(5-hydroxyindolyl)propionic acid
L-2-Amino-3-[3-(5-hydroxyindole)]propionic acid
L-5-Hydroxytryptophan hydrate, 98%
L-5-Hydroxytryptophan hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.58 | 1.2 | -34.71 | 5 | 5 | 0 | 104 | 220.228 | 3 | ↓ |
| Hi High (pH 8-9.5) | -1.58 | 0.89 | -50.08 | 4 | 5 | -1 | 102 | 219.22 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_source | Metab. of Chromobacterium violaceum, constit. of the seeds of Griffonia simplicifolia. Occurs in large amts. in Panaeolus sphinctrinus and other Panaeolus spp. | ZereneX Building Blocks |
| Melting_Point | 258? dec. | Alfa-Aesar |
| Melting_Point | 258° dec. | Alfa-Aesar |
| Mp [°C] | 270 | Acros Organics |
| MP | 270 °C (dec.)(lit.) | Indofine |
| MP | 273° | Matrix Scientific |
| ALOGPS_SOLUBILITY | 3.63e+00 g/l | DrugBank-nutriceuticals |
| Purity | 95% | Fluorochem |
| Purity | 95+% | Matrix Scientific |
| Purity | 98% | Fluorochem |
| Purity | 99% | APIChem |
| biological_use | Antidepressant | IBScreen Bioactives IBScreen Bioactives |
| Melting_Point | ca 298? dec. | Alfa-Aesar |
| Melting_Point | ca 298° dec. | Alfa-Aesar |
| UniProt Database Links | DDC_BOVIN; DDC_CAEEL; DDC_CATRO; DDC_CAVPO; DDC_DROLE; DDC_DROME; DDC_DROSI; DDC_HUMAN; DDC_MANSE; DDC_MOUSE; DDC_PIG; DDC_RAT; PH4H_DICDI; PH4H_DROME; TPH1_CHICK; TPH1_HUMAN; TPH1_MOUSE; TPH1_RABIT; TPH1_RAT; TPH2_HORSE; TPH2_HUMAN; TPH2_MACMU; TPH2_MOUS | ChEBI |
| SOLUBILITY | H2O: 10 mg/mL | Indofine |
| H phrase | H302: Harmful if swallowed | Acros Organics |
| Warnings | IRRITANT | Matrix Scientific |
| Target | Others | Selleck Chemicals |
| P phrase | P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell | Acros Organics |
| mechanism | Precusor of 5-hydroxytryptamine | IBScreen Bioactives |
| biological_use | Psychostimulant | IBScreen Bioactives |
| R phrase | R22: Harmful if swallowed. | Acros Organics |
| Reactome Database Links | REACT_15352; REACT_15546 | ChEBI |
| Hazard | XN: Harmful | Acros Organics |
| Description | Species |
|---|---|
| Serotonin and melatonin biosynthesis |
