| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 5th, 2007 | 25 | Yes |
Popular Name: (4-phenylpiperazin-1-yl)-(5-phenyl-2H-pyrazol-3-yl)-methanone (4-phenylpiperazin-1-yl)-(5-phen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.26 | 9.05 | -9.44 | 1 | 5 | 0 | 52 | 332.407 | 3 | ↓ |
| Ref Reference (pH 7) | 3.26 | 8.88 | -9.35 | 1 | 5 | 0 | 52 | 332.407 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NK3R-1-E | Neurokinin 3 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2100 | 0.32 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NK3R_HUMAN | P29371 | Neurokinin 3 Receptor, Human | 2100 | 0.32 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Tachykinin receptors bind tachykinins |
