UCSF

DNA Polymerase Delta Subunit 1, Human (1 Compounds)

Swissprot:
DPOD1_HUMAN
Stitch:
DPOD1_HUMAN
UniProt:
P28340
ChEMBL:
CHEMBL2735
Reactome:
REACT_160176
REACT_1838
REACT_228019
REACT_228145
REACT_1792
REACT_7987
REACT_8027
REACT_1385
REACT_2192
REACT_70
REACT_7999
REACT_1993
REACT_378
REACT_1128
REACT_7961
PDB:
POLD1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (15)

Reactome ID Description Species
REACT_160176 Cytosolic iron-sulfur cluster assembly Homo sapiens
REACT_1838 Leading Strand Synthesis Homo sapiens
REACT_228019 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) Homo sapiens
REACT_228145 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Homo sapiens
REACT_1792 Polymerase switching Homo sapiens
REACT_7987 Polymerase switching on the C-strand of the telomere Homo sapiens
REACT_8027 Processive synthesis on the C-strand of the telomere Homo sapiens
REACT_1385 Processive synthesis on the lagging strand Homo sapiens
REACT_2192 Removal of DNA patch containing abasic residue Homo sapiens
REACT_70 Removal of the Flap Intermediate Homo sapiens
REACT_7999 Removal of the Flap Intermediate from the C-strand Homo sapiens
REACT_1993 Repair synthesis for gap-filling by DNA polymerase in TC-NER Homo sapiens
REACT_378 Repair synthesis of patch ~27-30 bases long by DNA polymerase Homo sapiens
REACT_1128 Resolution of AP sites via the multiple-nucleotide patch replacement pathway Homo sapiens
REACT_7961 Telomere C-strand (Lagging Strand) Synthesis Homo sapiens

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
DPOL_HHV11 P04293 CHEMBL1872 Human Herpesvirus 1 DNA Polymerase, Hhv11 1
DPOL_HHV1K P04292 CHEMBL5944 DNA Polymerase Catalytic Subunit, Hhv1k 1
DPOL_VZVD P09252 CHEMBL4859 DNA Polymerase, Vzvd 1
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 1
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 1