| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 86 | 1 | 1 | 1 |
| Binding ≤ 1μM | 37 | 0 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_1095 | Activation of the pre-replicative complex | Homo sapiens |
| REACT_2244 | DNA replication initiation | Homo sapiens |
| REACT_471 | E2F mediated regulation of DNA replication | Homo sapiens |
| REACT_683 | G1/S-Specific Transcription | Homo sapiens |
| REACT_329 | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Homo sapiens |
| REACT_1838 | Leading Strand Synthesis | Homo sapiens |
| REACT_1792 | Polymerase switching | Homo sapiens |
| REACT_7987 | Polymerase switching on the C-strand of the telomere | Homo sapiens |
| REACT_1385 | Processive synthesis on the lagging strand | Homo sapiens |
| REACT_70 | Removal of the Flap Intermediate | Homo sapiens |
| REACT_7993 | Telomere C-strand synthesis initiation | Homo sapiens |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| DPOLA-1-E | DNA Polymerase Alpha Subunit (cluster #1 Of 2), Eukaryotic | 57 | 0 | 0 | 0 |
| DPOLA-2-E | DNA Polymerase Alpha Subunit (cluster #2 Of 2), Eukaryotic | 29 | 1 | 1 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| DPOLB_HUMAN | P06746 | CHEMBL2392 | DNA Polymerase Beta, Human | 24 |
| Z50606 | Z50606 | CHEMBL613497 | Hepatitis B Virus | 15 |
| DPOG1_HUMAN | P54098 | CHEMBL2732 | DNA Polymerase Gamma Subunit 1, Human | 12 |
| Q72547_9HIV1 | Q72547 | CHEMBL247 | Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 | 12 |
| KITH_RAT | P27158 | CHEMBL4022 | Thymidine Kinase, Rat | 3 |
| TDT_HUMAN | P04053 | CHEMBL4810 | Terminal Deoxynucleotidyltransferase, Human | 2 |
| DPOL_HCMVA | P08546 | CHEMBL3414 | Human Herpesvirus 5 DNA Polymerase, Hcmva | 1 |
| DPOL_HHV11 | P04293 | CHEMBL1872 | Human Herpesvirus 1 DNA Polymerase, Hhv11 | 1 |
| DPOL_HHV1K | P04292 | CHEMBL5944 | DNA Polymerase Catalytic Subunit, Hhv1k | 1 |
| DPOL_HHV6U | P28857 | CHEMBL4009 | Human Herpesvirus 6 DNA Polymerase, Hhv6u | 1 |
| DPOL_VZVD | P09252 | CHEMBL4859 | DNA Polymerase, Vzvd | 1 |
| Z50602 | Z50602 | CHEMBL377 | Human Herpesvirus 1 | 1 |
