|
Analogs
-
19850502
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 20 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
364 |
0.69 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
4800 |
0.57 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
364 |
0.69 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
4800 |
0.57 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
40 |
0.80 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
4800 |
0.57 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
40 |
0.80 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
4800 |
0.57 |
Binding ≤ 10μM
|
GRIK1-1-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
740 |
0.66 |
Binding ≤ 10μM
|
GRIK2-3-E |
Glutamate Receptor Ionotropic Kainate 2 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK3-3-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK4-1-E |
Glutamate Receptor Ionotropic Kainate 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3310 |
0.59 |
Functional ≤ 10μM
|
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
3310 |
0.59 |
Functional ≤ 10μM
|
GRIA3-1-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA4-1-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
800 |
0.66 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
4800 |
0.57 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
-2.69 |
-1.91 |
-52.1 |
3 |
6 |
-1 |
117 |
185.159 |
3 |
↓
|
Lo
Low (pH 4.5-6)
|
-2.69 |
-2.52 |
-37.61 |
4 |
6 |
0 |
114 |
186.167 |
3 |
↓
|
|
|
Analogs
-
19850499
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 23 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
22 |
0.82 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
364 |
0.69 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
17 |
0.84 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
364 |
0.69 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
21 |
0.83 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
40 |
0.80 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
40 |
0.80 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
40 |
0.80 |
Binding ≤ 10μM
|
GRIK1-1-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
740 |
0.66 |
Binding ≤ 10μM
|
GRIK1-1-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1150 |
0.64 |
Binding ≤ 10μM
|
GRIK2-3-E |
Glutamate Receptor Ionotropic Kainate 2 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK3-3-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK4-1-E |
Glutamate Receptor Ionotropic Kainate 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
12 |
0.85 |
Binding ≤ 10μM
|
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2144 |
0.61 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3310 |
0.59 |
Functional ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
3310 |
0.59 |
Functional ≤ 10μM
|
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA3-1-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA3-1-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA4-1-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIA4-1-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3500 |
0.59 |
Functional ≤ 10μM
|
GRIK3-1-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3800 |
0.58 |
Functional ≤ 10μM
|
Z104302-1-O |
Glutamate NMDA Receptor (cluster #1 Of 7), Other |
Other |
3500 |
0.59 |
Binding ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
800 |
0.66 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
6700 |
0.56 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
-2.69 |
-1.72 |
-76.52 |
3 |
6 |
-1 |
117 |
185.159 |
3 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 8 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRIA1-2-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
70 |
0.44 |
Binding ≤ 10μM |
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
70 |
0.44 |
Binding ≤ 10μM |
GRIA3-1-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
70 |
0.44 |
Binding ≤ 10μM |
GRIA4-1-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
70 |
0.44 |
Binding ≤ 10μM |
GRIK1-2-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
8000 |
0.31 |
Binding ≤ 10μM |
GRIK2-1-E |
Glutamate Receptor Ionotropic Kainate 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8000 |
0.31 |
Binding ≤ 10μM |
GRIK3-1-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8000 |
0.31 |
Binding ≤ 10μM |
GRIK4-1-E |
Glutamate Receptor Ionotropic Kainate 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
8000 |
0.31 |
Binding ≤ 10μM |
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
79 |
0.43 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
6000 |
0.32 |
Functional ≤ 10μM
|
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
2500 |
0.34 |
Functional ≤ 10μM
|
GRIA3-1-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
200 |
0.41 |
Functional ≤ 10μM
|
GRIA4-1-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
200 |
0.41 |
Functional ≤ 10μM
|
GRIK1-1-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
90 |
0.43 |
Functional ≤ 10μM
|
GRIK2-1-E |
Glutamate Receptor Ionotropic Kainate 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
90 |
0.43 |
Functional ≤ 10μM
|
GRIK3-1-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
90 |
0.43 |
Functional ≤ 10μM
|
GRIK4-1-E |
Glutamate Receptor Ionotropic Kainate 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
90 |
0.43 |
Functional ≤ 10μM
|
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
90 |
0.43 |
Functional ≤ 10μM
|
Z104302-4-O |
Glutamate NMDA Receptor (cluster #4 Of 7), Other |
Other |
200 |
0.41 |
Binding ≤ 10μM
|
Z50594-1-O |
Mus Musculus (cluster #1 Of 9), Other |
Other |
300 |
0.40 |
Functional ≤ 10μM |
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
4000 |
0.33 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
-0.57 |
1.41 |
-25.8 |
4 |
10 |
0 |
172 |
336.285 |
2 |
↓
|
Mid
Mid (pH 6-8)
|
0.33 |
-0.74 |
-49.41 |
3 |
10 |
-1 |
175 |
335.277 |
2 |
↓
|
Mid
Mid (pH 6-8)
|
0.33 |
-0.78 |
-57.47 |
3 |
10 |
-1 |
175 |
335.277 |
2 |
↓
|
|
|
Analogs
-
22066252
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 9 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
FOLH1-1-E |
Glutamate Carboxypeptidase II (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9500 |
0.54 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
80 |
0.76 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
80 |
0.76 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
80 |
0.76 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
80 |
0.76 |
Binding ≤ 10μM
|
GRIK1-3-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
171 |
0.73 |
Binding ≤ 10μM
|
GRIK2-3-E |
Glutamate Receptor Ionotropic Kainate 2 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
150 |
0.73 |
Binding ≤ 10μM
|
GRIK3-3-E |
Glutamate Receptor Ionotropic Kainate 3 (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
1670 |
0.62 |
Binding ≤ 10μM
|
GRIK4-2-E |
Glutamate Receptor Ionotropic Kainate 4 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
150 |
0.73 |
Binding ≤ 10μM
|
GRIK5-1-E |
Glutamate Receptor Ionotropic Kainate 5 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
150 |
0.73 |
Binding ≤ 10μM
|
GRM1-2-E |
Metabotropic Glutamate Receptor 1 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
GRM3-1-E |
Metabotropic Glutamate Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
GRM5-2-E |
Metabotropic Glutamate Receptor 5 (cluster #2 Of 5), Eukaryotic |
Eukaryotes |
150 |
0.73 |
Binding ≤ 10μM
|
GRM7-1-E |
Metabotropic Glutamate Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
GRM8-2-E |
Metabotropic Glutamate Receptor 8 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
Q80T35-1-E |
Metabotropic Glutamate Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
Q80T43-1-E |
Metabotropic Glutamate Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
Q80T47-1-E |
Metabotropic Glutamate Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.82 |
Binding ≤ 10μM
|
XCT-1-E |
Cystine/glutamate Transporter (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5000 |
0.57 |
Binding ≤ 10μM
|
GRM1-3-E |
Metabotropic Glutamate Receptor 1 (cluster #3 Of 5), Eukaryotic |
Eukaryotes |
1100 |
0.64 |
Functional ≤ 10μM
|
GRM5-4-E |
Metabotropic Glutamate Receptor 5 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
55 |
0.78 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
7300 |
0.55 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
-4.04 |
-4.9 |
-43.55 |
3 |
8 |
-1 |
139 |
188.119 |
3 |
↓
|
Hi
High (pH 8-9.5)
|
-4.04 |
-5.21 |
-87.71 |
2 |
8 |
-2 |
137 |
187.111 |
3 |
↓
|
Mid
Mid (pH 6-8)
|
-4.04 |
-7.81 |
-15.85 |
4 |
8 |
0 |
132 |
189.127 |
3 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 1 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
170 |
0.73 |
Binding ≤ 10μM
|
GRIA1-1-E |
Glutamate Receptor Ionotropic, AMPA 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
340 |
0.70 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
250 |
0.71 |
Binding ≤ 10μM
|
GRIA2-4-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
340 |
0.70 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
340 |
0.70 |
Binding ≤ 10μM
|
GRIA3-4-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #4 Of 4), Eukaryotic |
Eukaryotes |
600 |
0.67 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
340 |
0.70 |
Binding ≤ 10μM
|
GRIA4-4-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic |
Eukaryotes |
600 |
0.67 |
Binding ≤ 10μM
|
GRIK1-1-E |
Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
4800 |
0.57 |
Binding ≤ 10μM
|
GRM1-2-E |
Metabotropic Glutamate Receptor 1 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
GRM1-2-E |
Metabotropic Glutamate Receptor 1 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
GRM3-1-E |
Metabotropic Glutamate Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
GRM3-1-E |
Metabotropic Glutamate Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
GRM7-1-E |
Metabotropic Glutamate Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
GRM7-1-E |
Metabotropic Glutamate Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
GRM8-2-E |
Metabotropic Glutamate Receptor 8 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
GRM8-2-E |
Metabotropic Glutamate Receptor 8 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
Q80T35-1-E |
Metabotropic Glutamate Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
Q80T35-1-E |
Metabotropic Glutamate Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
Q80T43-1-E |
Metabotropic Glutamate Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
Q80T43-1-E |
Metabotropic Glutamate Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
Q80T47-1-E |
Metabotropic Glutamate Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.72 |
Binding ≤ 10μM
|
Q80T47-1-E |
Metabotropic Glutamate Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.72 |
Binding ≤ 10μM
|
GRIA2-1-E |
Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
5400 |
0.57 |
Functional ≤ 10μM
|
GRIA3-2-E |
Glutamate Receptor Ionotropic, AMPA 3 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
600 |
0.67 |
Functional ≤ 10μM
|
GRIA4-2-E |
Glutamate Receptor Ionotropic, AMPA 4 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
600 |
0.67 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
200 |
0.72 |
Functional ≤ 10μM
|
Z50597-1-O |
Rattus Norvegicus (cluster #1 Of 12), Other |
Other |
220 |
0.72 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
-2.32 |
-0.57 |
-40.2 |
3 |
6 |
-1 |
112 |
250.028 |
3 |
↓
|
Mid
Mid (pH 6-8)
|
-1.86 |
-2.1 |
-91.82 |
2 |
6 |
-2 |
115 |
249.02 |
3 |
↓
|
Lo
Low (pH 4.5-6)
|
-2.32 |
-0.24 |
-33.53 |
4 |
6 |
0 |
114 |
251.036 |
3 |
↓
|
|