UCSF

Eukaryotic Translation Initation Factor, Human (3 Compounds)

Swissprot:
IF4E_HUMAN
Stitch:
IF4E_HUMAN
UniProt:
P06730
ChEMBL:
CHEMBL4848
Reactome:
REACT_1258
REACT_20514
REACT_2085
REACT_115831
REACT_79
REACT_6836
REACT_931
REACT_1979
REACT_1597
REACT_1835
REACT_405
REACT_424
PDB:
1IPB (DOCK)
1IPC (DOCK)
1WKW (DOCK)
2GPQ (DOCK)
2V8W (DOCK)
2V8X (DOCK)
2V8Y (DOCK)
2W97 (DOCK)
3AM7 (DOCK)
3TF2 (DOCK)
3U7X (DOCK)
EIF4E

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (12)

Reactome ID Description Species
REACT_1258 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and sub Homo sapiens
REACT_20514 Deadenylation of mRNA Homo sapiens
REACT_2085 GTP hydrolysis and joining of the 60S ribosomal subunit Homo sapiens
REACT_115831 ISG15 antiviral mechanism Homo sapiens
REACT_79 L13a-mediated translational silencing of Ceruloplasmin expression Homo sapiens
REACT_6836 Release of eIF4E Homo sapiens
REACT_931 Ribosomal scanning and start codon recognition Homo sapiens
REACT_1979 Translation initiation complex formation Homo sapiens
REACT_1597 Transport of Mature mRNA derived from an Intron-Containing Transcript Homo sapiens
REACT_1835 Transport of Mature mRNA Derived from an Intronless Transcript Homo sapiens
REACT_405 Transport of the SLBP Dependant Mature mRNA Homo sapiens
REACT_424 Transport of the SLBP independent Mature mRNA Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
IF4E_MOUSE P63073 CHEMBL6148 Eukaryotic Translation Initiation Factor 4E, Mouse 15 1 1 0
IF4E_RABIT P29338 CHEMBL5636 Eukaryotic Translation Initiation Factor 4E, Rabit 2 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
IF4E_MOUSE P63073 CHEMBL6148 Eukaryotic Translation Initiation Factor 4E, Mouse 1