UCSF

Eukaryotic Translation Initiation Factor 4E, Mouse (15 Compounds)

Swissprot:
IF4E_MOUSE
Stitch:
IF4E_MOUSE
UniProt:
P63073
ChEMBL:
CHEMBL6148
Reactome:
REACT_255163
REACT_244119
REACT_262078
REACT_198533
REACT_259469
REACT_241655
REACT_236458
REACT_256488
REACT_232353
REACT_244199
REACT_239127
REACT_212343
PDB:
1EJ1 (DOCK)
1EJ4 (DOCK)
1EJH (DOCK)
1L8B (DOCK)
Eif4e

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 15 1 1 0
Binding ≤ 1μM 3 1 0 0

Reactome Network (12)

Reactome ID Description Species
REACT_255163 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and sub Mus musculus
REACT_244119 Deadenylation of mRNA Mus musculus
REACT_262078 GTP hydrolysis and joining of the 60S ribosomal subunit Mus musculus
REACT_198533 ISG15 antiviral mechanism Mus musculus
REACT_259469 L13a-mediated translational silencing of Ceruloplasmin expression Mus musculus
REACT_241655 Release of eIF4E Mus musculus
REACT_236458 Ribosomal scanning and start codon recognition Mus musculus
REACT_256488 Translation initiation complex formation Mus musculus
REACT_232353 Transport of Mature mRNA derived from an Intron-Containing Transcript Mus musculus
REACT_244199 Transport of Mature mRNA Derived from an Intronless Transcript Mus musculus
REACT_239127 Transport of the SLBP Dependant Mature mRNA Mus musculus
REACT_212343 Transport of the SLBP independent Mature mRNA Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
IF4E_HUMAN P06730 CHEMBL4848 Eukaryotic Translation Initation Factor, Human 3 0 0 0
IF4E_RABIT P29338 CHEMBL5636 Eukaryotic Translation Initiation Factor 4E, Rabit 2 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
IF4E_HUMAN P06730 CHEMBL4848 Eukaryotic Translation Initation Factor, Human 1