UCSF

Histone Acetyltransferase PCAF, Human (41 Compounds)

Swissprot:
KAT2B_HUMAN
Stitch:
KAT2B_HUMAN
UniProt:
Q92831
ChEMBL:
CHEMBL5500
Reactome:
REACT_160254
REACT_160243
REACT_172610
REACT_14835
REACT_118780
REACT_118568
REACT_953
REACT_118713
PDB:
1CM0 (DOCK)
1JM4 (DOCK)
1N72 (DOCK)
1WUG (DOCK)
1WUM (DOCK)
1ZS5 (DOCK)
2RNW (DOCK)
2RNX (DOCK)
3GG3 (DOCK)
KAT2B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 41 4 1 0
Binding ≤ 1μM 2 0 0 0

Reactome Network (8)

Reactome ID Description Species
REACT_160254 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Homo sapiens
REACT_160243 Constitutive Signaling by NOTCH1 PEST Domain Mutants Homo sapiens
REACT_172610 HATs acetylate histones Homo sapiens
REACT_14835 Notch-HLH transcription pathway Homo sapiens
REACT_118780 NOTCH1 Intracellular Domain Regulates Transcription Homo sapiens
REACT_118568 Pre-NOTCH Transcription and Translation Homo sapiens
REACT_953 RNA Polymerase I Transcription Initiation Homo sapiens
REACT_118713 YAP1- and WWTR1 (TAZ)-stimulated gene expression Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3

Constitutive Signaling by NOTCH1 PEST Domain Mutants

Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3

HATs acetylate histones

Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3

NOTCH1 Intracellular Domain Regulates Transcription

Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3

Pre-NOTCH Transcription and Translation

Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
KAT2B-1-E Histone Acetyltransferase PCAF (cluster #1 Of 2), Eukaryotic 40 4 1 0
KAT2B-2-E Histone Acetyltransferase PCAF (cluster #2 Of 2), Eukaryotic 1 0 0 0
Uniprot Swissprot Chembl Description Number Shared
EP300_HUMAN Q09472 CHEMBL3784 Histone Acetyltransferase P300, Human 3
ATP4A_PIG P19156 CHEMBL3919 Potassium-transporting ATPase Alpha Chain 1, Pig 1
ATP4B_PIG P18434 CHEMBL2538 Potassium-transporting ATPase Beta Chain, Pig 1