UCSF

Thymidine Kinase, Cytosolic, Human (42 Compounds)

Swissprot:
KITH_HUMAN
Stitch:
KITH_HUMAN
UniProt:
P04183
ChEMBL:
CHEMBL2883
Reactome:
REACT_655
PDB:
1W4R (DOCK)
1XBT (DOCK)
2ORV (DOCK)
2WVJ (DOCK)
TK1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 42 12 6 8
Binding ≤ 1μM 15 5 4 6
Functional ≤ 10μM 3 1 1 1

Reactome Network (1)

Reactome ID Description Species
REACT_655 Pyrimidine salvage reactions Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KITM_HUMAN O00142 CHEMBL4580 Thymidine Kinase, Mitochondrial, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KITH_HHV1 Q9QNF7 CHEMBL1795127 Thymidine Kinase, Hhv1 3 0 0 0
KITH_HHV1S P06479 CHEMBL1820 Thymidine Kinase, Hhv1s 142 2 3 8
KITH_MOUSE P04184 CHEMBL2618 Thymidine Kinase, Cytosolic, Mouse 0 0 0 0
KITH_RAT P27158 CHEMBL4022 Thymidine Kinase, Rat 11 4 0 0
KITH_VZVD P09250 CHEMBL4784 Thymidine Kinase, Vzvd 9 0 1 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
KITH-1-E Thymidine Kinase (cluster #1 Of 2), Eukaryotic 49 16 6 8
KITH-1-V Thymidine Kinase (cluster #1 Of 1), Viral 151 2 3 8
KITH-2-E Thymidine Kinase (cluster #2 Of 2), Eukaryotic 4 0 0 0
Uniprot Swissprot Chembl Description Number Shared
KITH_HHV1S P06479 CHEMBL1820 Thymidine Kinase, Hhv1s 3
A3RLP8_CHV1 A3RLP8 CHEMBL1075062 Thymidine Kinase, Chv1 2
DNK_DROME Q9XZT6 CHEMBL4760 Deoxynucleoside Kinase, Drome 1
KITM_HUMAN O00142 CHEMBL4580 Thymidine Kinase, Mitochondrial, Human 1
KTHY_MYCTU O05891 CHEMBL2361 Thymidylate Kinase, Myctu 1
Q6L709_HHV2 Q6L709 CHEMBL3415 Thymidine Kinase, Hhv2 1
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 1
Z50606 Z50606 CHEMBL613497 Hepatitis B Virus 1
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 1
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 1