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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

34348601
34348601
2585428
2585428
5157283
5157283

Draw Identity 99% 90% 80% 70%

Popular Name: 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL HYDROCHLORIDE 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
MA2C1-1-E Alpha-mannosidase 2C1 (cluster #1 Of 1), Eukaryotic Eukaryotes 500 0.80 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -2.62 -10.49 -47.04 6 5 1 97 164.181 2 ↓

Analogs

13327722
13327722
36466200
36466200

Draw Identity 99% 90% 80% 70%

Popular Name: 3,4-Pyrrolidinediol, 2-(1-hydroxyethyl)-, [2R-[2alpha(S*),3alpha,4alpha]]- (9CI) 3,4-Pyrrolidinediol, 2-(1-hydrox…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
MA2C1-1-E Alpha-mannosidase 2C1 (cluster #1 Of 1), Eukaryotic Eukaryotes 600 0.87 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.61 -7.15 -41.87 5 4 1 77 148.182 1 ↓

Analogs

33961860
33961860

Draw Identity 99% 90% 80% 70%

Popular Name: swainsonine swainsonine

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And 5 More

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
MA122-1-E Mannosyl-oligosaccharide Alpha-1,2-mannosidase Isoform B (cluster #1 Of 1), Eukaryotic Eukaryotes 5 0.97 Binding ≤ 10μM
MA2A1-1-E Alpha-mannosidase 2A1 (cluster #1 Of 1), Eukaryotic Eukaryotes 10000 0.58 Binding ≤ 10μM
MA2B1-1-E Lysosomal Alpha-mannosidase (cluster #1 Of 1), Eukaryotic Eukaryotes 50 0.85 Binding ≤ 10μM
MA2C1-1-E Alpha-mannosidase 2C1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1750 0.67 Binding ≤ 10μM
MA2C1-1-E Alpha-mannosidase 2C1 (cluster #1 Of 1), Eukaryotic Eukaryotes 10000 0.58 Binding ≤ 10μM
Q9SEH8-1-E Alpha-mannosidase (cluster #1 Of 1), Eukaryotic Eukaryotes 400 0.75 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.34 -2.96 -32.36 4 4 1 65 174.22 0 ↓

Analogs

33961860
33961860

Draw Identity 99% 90% 80% 70%

Popular Name: Swainsonine Swainsonine

Find On: PubMed — Wikipedia — Google

Vendors

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
MA2A1-1-E Alpha-mannosidase 2A1 (cluster #1 Of 1), Eukaryotic Eukaryotes 10000 0.58 Binding ≤ 10μM
MA2C1-1-E Alpha-mannosidase 2C1 (cluster #1 Of 1), Eukaryotic Eukaryotes 10000 0.58 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.34 -2.74 -31.11 4 4 1 65 174.22 0 ↓

Parameters Provided:

annotation.name = MA2C1_RAT
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'MA2C1\\_RAT' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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