UCSF

Sodium/glucose Cotransporter 1, Human (153 Compounds)

Swissprot:
SC5A1_HUMAN
Stitch:
SC5A1_HUMAN
UniProt:
P13866
ChEMBL:
CHEMBL4979
Reactome:
REACT_9441
REACT_19188
REACT_19165
PDB:
SLC5A1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 153 5 4 1
Binding ≤ 1μM 60 3 2 1
Functional ≤ 10μM 16 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_9441 Hexose transport Homo sapiens
REACT_19188 Inositol transporters Homo sapiens
REACT_19165 Na+-dependent glucose transporters Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 15

Inositol transporters

Uniprot Swissprot Chembl Description Number Shared
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 15
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2

Na+-dependent glucose transporters

Uniprot Swissprot Chembl Description Number Shared
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 15
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC5A1_RAT P53790 CHEMBL5374 Sodium/glucose Cotransporter 1, Rat 1 1 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 576 14 5 1
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 30 3 2 1
SC5A7_HUMAN Q9GZV3 CHEMBL4507 High-affinity Choline Transporter, Human 2 1 0 0
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2 1 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
SC5A1-1-E Sodium/glucose Cotransporter 1 (cluster #1 Of 2), Eukaryotic 149 5 4 1
SC5A1-2-E Sodium/glucose Cotransporter 1 (cluster #2 Of 2), Eukaryotic 4 0 0 0
Uniprot Swissprot Chembl Description Number Shared
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 15
SC5A2_MOUSE Q923I7 CHEMBL1075302 Sodium/glucose Cotransporter 2, Mouse 3
SC5A2_RAT P53792 CHEMBL4316 Sodium/glucose Cotransporter 2, Rat 3
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2
Q9QXI6_MOUSE Q9QXI6 CHEMBL1744523 SGLT1 Protein, Mouse 1
SC5A1_RAT P53790 CHEMBL5374 Sodium/glucose Cotransporter 1, Rat 1

Most Common Rings