UCSF

Signal Transducer And Activator Of Transcription 5A, Human (2 Compounds)

Swissprot:
STA5A_HUMAN
Stitch:
STA5A_HUMAN
UniProt:
P42229
ChEMBL:
CHEMBL5403
Reactome:
REACT_17025
REACT_111133
REACT_27283
REACT_23837
REACT_115529
REACT_116022
REACT_115697
REACT_121141
REACT_169118
REACT_111040
PDB:
STAT5A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2 1 0 0
Binding ≤ 1μM 2 1 0 0

Reactome Network (10)

Reactome ID Description Species
REACT_17025 Downstream signal transduction Homo sapiens
REACT_111133 Growth hormone receptor signaling Homo sapiens
REACT_27283 Interleukin-2 signaling Homo sapiens
REACT_23837 Interleukin-3, 5 and GM-CSF signaling Homo sapiens
REACT_115529 Interleukin-7 signaling Homo sapiens
REACT_116022 Nuclear signaling by ERBB4 Homo sapiens
REACT_115697 Prolactin receptor signaling Homo sapiens
REACT_121141 Signaling by FGFR1 fusion mutants Homo sapiens
REACT_169118 Signaling by Leptin Homo sapiens
REACT_111040 Signaling by SCF-KIT Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1

Growth hormone receptor signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1

Interleukin-2 signaling

Uniprot Swissprot Chembl Description Number Shared
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1

Interleukin-3, 5 and GM-CSF signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1

Interleukin-7 signaling

Uniprot Swissprot Chembl Description Number Shared
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2

Prolactin receptor signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1

Signaling by FGFR1 fusion mutants

Uniprot Swissprot Chembl Description Number Shared
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1

Signaling by Leptin

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1

Signaling by SCF-KIT

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 1