UCSF

Transcription Factor 7, Human (1 Compounds)

Swissprot:
TCF7_HUMAN
Stitch:
TCF7_HUMAN
UniProt:
P36402
ChEMBL:
CHEMBL1075124
Reactome:
REACT_200799
REACT_172761
REACT_200731
REACT_200753
REACT_228106
PDB:
TCF7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_200799 binding of TCF/LEF:CTNNB1 to target gene promoters Homo sapiens
REACT_172761 Ca2+ pathway Homo sapiens
REACT_200731 deactivation of the beta-catenin transactivating complex Homo sapiens
REACT_200753 formation of the beta-catenin:TCF transactivating complex Homo sapiens
REACT_228106 repression of WNT target genes Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1

Ca2+ pathway

Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1

deactivation of the beta-catenin transactivating complex

Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1

formation of the beta-catenin:TCF transactivating complex

Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1

repression of WNT target genes

Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CTNB1_HUMAN P35222 CHEMBL5866 Catenin Beta-1, Human 1
PSMG1_HUMAN O95456 CHEMBL1075122 Proteasome Assembly Chaperone 1, Human 1
PSMG2_HUMAN Q969U7 CHEMBL1075123 Proteasome Assembly Chaperone 2, Human 1
PSMG3_HUMAN Q9BT73 CHEMBL1075137 Proteasome Assembly Chaperone 3, Human 1