UCSF

Low Affinity Neurotrophin Receptor P75NTR, Human (5 Compounds)

Swissprot:
TNR16_HUMAN
Stitch:
TNR16_HUMAN
UniProt:
P08138
ChEMBL:
CHEMBL4762
Reactome:
REACT_13815
REACT_13779
REACT_13806
REACT_13526
REACT_13696
REACT_13724
REACT_13638
REACT_13643
REACT_13695
REACT_13415
REACT_13443
PDB:
3EWV (DOCK)
NGFR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 5 1 0 0
Binding ≤ 1μM 1 0 0 0

Reactome Network (11)

Reactome ID Description Species
REACT_13815 Axonal growth inhibition (RHOA activation) Homo sapiens
REACT_13779 Axonal growth stimulation Homo sapiens
REACT_13806 Ceramide signalling Homo sapiens
REACT_13526 NADE modulates death signalling Homo sapiens
REACT_13696 NF-kB is activated and signals survival Homo sapiens
REACT_13724 NFG and proNGF binds to p75NTR Homo sapiens
REACT_13638 NRAGE signals death through JNK Homo sapiens
REACT_13643 NRIF signals cell death from the nucleus Homo sapiens
REACT_13695 p75NTR negatively regulates cell cycle via SC1 Homo sapiens
REACT_13415 p75NTR recruits signalling complexes Homo sapiens
REACT_13443 Regulated proteolysis of p75NTR Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TNR1A_HUMAN P19438 CHEMBL3378 Tumor Necrosis Factor Receptor R1, Human 30 6 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1