UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 5-(phenylmethyl)-2,4(1h,3h)-pyrimidinedione 5-(phenylmethyl)-2,4(1h,3h)-pyri…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
UPP1-1-E Uridine Phosphorylase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1000 0.56 Binding ≤ 10μM
UPP2-1-E Uridine Phosphorylase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 1000 0.56 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.04 -1.88 -15.15 2 4 0 65 202.213 2 ↓

Analogs

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Popular Name: 5-benzyloxybenzylacyclouridine 5-benzyloxybenzylacyclouridine

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
UPP1-1-E Uridine Phosphorylase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 84 0.35 Binding ≤ 10μM
UPP2-1-E Uridine Phosphorylase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 84 0.35 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.15 -3.95 -26.22 2 7 0 93 382.416 9 ↓

Parameters Provided:

annotation.name = UPP1_MOUSE
anotation.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN note AS n ON ci.sub_id_fk=n.sub_id_fk INNER JOIN annotation AS a ON n.anno_id_fk=a.anno_id  WHERE c.free = 1 AND a.short_desc LIKE 'UPP1\\_MOUSE' AND c.purchasable IN (1,2,4,5)    LIMIT 50

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