ZINC 12

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ACM1-5-E	Muscarinic Acetylcholine Receptor M1 (cluster #5 Of 5), Eukaryotic	Eukaryotes	7943	0.65	Binding ≤ 10μM
ACM2-2-E	Muscarinic Acetylcholine Receptor M2 (cluster #2 Of 6), Eukaryotic	Eukaryotes	955	0.77	Binding ≤ 10μM
ACM3-5-E	Muscarinic Acetylcholine Receptor M3 (cluster #5 Of 5), Eukaryotic	Eukaryotes	6166	0.66	Binding ≤ 10μM
ACM4-4-E	Muscarinic Acetylcholine Receptor M4 (cluster #4 Of 6), Eukaryotic	Eukaryotes	6310	0.66	Binding ≤ 10μM
ACM5-4-E	Muscarinic Acetylcholine Receptor M5 (cluster #4 Of 4), Eukaryotic	Eukaryotes	6918	0.66	Binding ≤ 10μM
Z104303-7-O	Muscarinic Acetylcholine Receptor (cluster #7 Of 7), Other	Other	6	1.05	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-2.56	7.34	-31.18	0	2	1	13	154.233	2	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

target.name = Z104303-7-O
target.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN activity AS ac ON ci.sub_id_fk=ac.sub_id_fk INNER JOIN target AS t ON ac.target_fk=t.target_id  WHERE c.free = 1 AND t.code LIKE 'Z104303-7-O' AND t.atype_fk = 0 AND c.purchasable IN (1,2,4,5)    LIMIT 50

Permalink

//zinc12.docking.org/results/combination?target.name=Z104303-7-O&target.type=B10&filter.purchasability=purchasable

Embed Link to Results

<div id="zinc-link"></div>
<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
<script type="text/javascript">
    window.zinc.embed('zinc-link', {
        "target.name": "Z104303-7-O",        
        "target.type": "B10"        

    });
</script>

ZINC 12

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Physical Representations

Parameters Provided:

Structural Results Found: (before additional filtering)

SQL Query Was

Permalink

Embed Link to Results