Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.55	9.72	-88.6	8	9	1	167	516.622	10	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	0.55	8.62	-88.1	7	9	0	162	515.614	10	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
PROC-1-E	Vitamin K-dependent Protein C (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.24	Binding ≤ 10μM
THRB-1-E	Prothrombin (cluster #1 Of 8), Eukaryotic	Eukaryotes	770	0.23	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
THRB_HUMAN	P00734	Thrombin, Human	770	0.23	Binding ≤ 1μM
PROC_HUMAN	P04070	Vitamin K-dependent Protein C, Human	250	0.24	Binding ≤ 1μM
THRB_HUMAN	P00734	Thrombin, Human	770	0.23	Binding ≤ 10μM
PROC_HUMAN	P04070	Vitamin K-dependent Protein C, Human	250	0.24	Binding ≤ 10μM

Description	Species
Cell surface interactions at the vascular wall	Homo sapiens (THRB_HUMAN)
Common Pathway	Homo sapiens (THRB_HUMAN)
G alpha (q) signalling events	Homo sapiens (THRB_HUMAN)
Gamma-carboxylation of protein precursors	Homo sapiens (THRB_HUMAN)
Intrinsic Pathway	Homo sapiens (THRB_HUMAN)
Peptide ligand-binding receptors	Homo sapiens (THRB_HUMAN)
Platelet Aggregation (Plug Formation)	Homo sapiens (THRB_HUMAN)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l	Homo sapiens (THRB_HUMAN)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Homo sapiens (THRB_HUMAN)
Thrombin signalling through proteinase activated receptors (PARs)	Homo sapiens (THRB_HUMAN)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu	Homo sapiens (THRB_HUMAN)