| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 23rd, 2009 | 39 | No |
Popular Name: tert-butyl tert-butyl
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.22 | 6.57 | -20.93 | 3 | 10 | 0 | 120 | 573.119 | 6 | ↓ |
| Mid Mid (pH 6-8) | 3.22 | 9 | -53.86 | 4 | 10 | 1 | 121 | 574.127 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10-1-E | Coagulation Factor X (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 10 | 0.29 | Binding ≤ 1μM |
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 10 | 0.29 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Common Pathway | |
| Extrinsic Pathway | |
| Gamma-carboxylation of protein precursors | |
| Intrinsic Pathway | |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |
![4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine](http://zinc12.docking.org/img/rings/4740.gif)
![N-[4-(1H-indole-2-carbonylamino)-3-piperidyl]-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide](http://zinc12.docking.org/img/rings/67285.gif)
