UCSF

Cathepsin L, Rat (26 Compounds)

Swissprot:
CATL1_RAT
Stitch:
CATL1_RAT
UniProt:
P07154
ChEMBL:
CHEMBL2305
Reactome:
REACT_198590
REACT_199129
REACT_199178
REACT_198830

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 26 0 0 1
Binding ≤ 1μM 19 0 0 1

Reactome Network (4)

Reactome ID Description Species
REACT_198590 Activation of Matrix Metalloproteinases Rattus norvegicus
REACT_199129 Assembly of collagen fibrils and other multimeric structures Rattus norvegicus
REACT_199178 Degradation of the extracellular matrix Rattus norvegicus
REACT_198830 MHC class II antigen presentation Rattus norvegicus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CATL1_BOVIN P25975 CHEMBL2113 Cathepsin L, Bovin 29 5 0 0
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 980 26 7 16
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9 0 0 1

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
CATL1-1-E Cathepsin L (cluster #1 Of 5), Eukaryotic 881 23 5 13
CATL1-2-E Cathepsin L (cluster #2 Of 5), Eukaryotic 4 2 2 2
CATL1-3-E Cathepsin L (cluster #3 Of 5), Eukaryotic 15 1 0 0
CATL1-4-E Cathepsin L (cluster #4 Of 5), Eukaryotic 8 1 0 0
CATL1-5-E Cathepsin L (cluster #5 Of 5), Eukaryotic 121 2 0 1
Uniprot Swissprot Chembl Description Number Shared
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 23
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 21
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 17
CATB_MOUSE P10605 CHEMBL5187 Cathepsin B, Mouse 9
CATB_RAT P00787 CHEMBL2602 Cathepsin B, Rat 9
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 9
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9
CATS_MOUSE O70370 CHEMBL4098 Cathepsin S, Mouse 9
CATS_RAT Q02765 CHEMBL1075217 Cathepsin S, Rat 9
CATK_MOUSE P55097 CHEMBL1075277 Cathepsin K, Mouse 7
CATK_RABIT P43236 CHEMBL3349 Cathepsin K, Rabit 1