UCSF

Cathepsin S, Mouse (25 Compounds)

Swissprot:
CATS_MOUSE
Stitch:
CATS_MOUSE
UniProt:
O70370
ChEMBL:
CHEMBL4098
Reactome:
REACT_199046
REACT_199052
REACT_199112
REACT_196550
REACT_198976
PDB:
1M0H (DOCK)
Ctss

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 25 1 0 2
Binding ≤ 1μM 23 1 0 2

Reactome Network (5)

Reactome ID Description Species
REACT_199046 Assembly of collagen fibrils and other multimeric structures Mus musculus
REACT_199052 Degradation of the extracellular matrix Mus musculus
REACT_199112 Endosomal/Vacuolar pathway Mus musculus
REACT_196550 MHC class II antigen presentation Mus musculus
REACT_198976 Trafficking and processing of endosomal TLR Mus musculus
Uniprot Swissprot Chembl Description Number Shared
CATB_MOUSE P10605 CHEMBL5187 Cathepsin B, Mouse 11
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9

Degradation of the extracellular matrix

Uniprot Swissprot Chembl Description Number Shared
CATK_MOUSE P55097 CHEMBL1075277 Cathepsin K, Mouse 9
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9

MHC class II antigen presentation

Uniprot Swissprot Chembl Description Number Shared
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9

Trafficking and processing of endosomal TLR

Uniprot Swissprot Chembl Description Number Shared
CATB_MOUSE P10605 CHEMBL5187 Cathepsin B, Mouse 11
CATK_MOUSE P55097 CHEMBL1075277 Cathepsin K, Mouse 9
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 1,468 15 5 14
CATS_RAT Q02765 CHEMBL1075217 Cathepsin S, Rat 9 0 0 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CATS-1-E Cathepsin S (cluster #1 Of 2), Eukaryotic 629 0 0 2
CATS-2-E Cathepsin S (cluster #2 Of 2), Eukaryotic 844 15 5 12
Uniprot Swissprot Chembl Description Number Shared
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 24
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 23
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 17
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 16
CATB_MOUSE P10605 CHEMBL5187 Cathepsin B, Mouse 11
CATB_RAT P00787 CHEMBL2602 Cathepsin B, Rat 9
CATK_MOUSE P55097 CHEMBL1075277 Cathepsin K, Mouse 9
CATL1_MOUSE P06797 CHEMBL5291 Cathepsin L1, Mouse 9
CATL1_RAT P07154 CHEMBL2305 Cathepsin L, Rat 9
CATS_RAT Q02765 CHEMBL1075217 Cathepsin S, Rat 9
CATK_RABIT P43236 CHEMBL3349 Cathepsin K, Rabit 6
CATC_HUMAN P53634 CHEMBL2252 Dipeptidyl Peptidase I, Human 1

Most Common Rings