UCSF
Image of 7H-pyrrolo[2,3-d]pyrimidine

Identity 99% 90% 80% 70% Substructure

7H-pyrrolo[2,3-d]pyrimidine

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 9 6 3 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 0 394 120 5 1 2012-03-07

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 53 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 49 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50530 Z50530 CHEMBL371 Human Herpesvirus 5 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80954 Z80954 CHEMBL614071 HFF (Foreskin Fibroblasts) 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50527 Z50527 CHEMBL613132 Human Herpesvirus 3 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATS_MOUSE O70370 CHEMBL4098 Cathepsin S, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATS_MOUSE O70370 CHEMBL4098 Cathepsin S, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_PNECA P16184 CHEMBL1926 Dihydrofolate Reductase, Pneca 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_PNECA P16184 CHEMBL1926 Dihydrofolate Reductase, Pneca 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z103205 Z103205 CHEMBL1075390 A431 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587 Z50587 CHEMBL372 Homo Sapiens 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80657 Z80657 CHEMBL614255 A253 Cell Line 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80847 Z80847 CHEMBL612250 FaDu (Pharyngeal Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase