UCSF

Sodium Channel Protein Type V Alpha Subunit, Human (81 Compounds)

Swissprot:
SCN5A_HUMAN
Stitch:
SCN5A_HUMAN
UniProt:
Q14524
ChEMBL:
CHEMBL1980
Reactome:
REACT_22266
PDB:
2KBI (DOCK)
2L53 (DOCK)
SCN5A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 81 10 5 6
Binding ≤ 1μM 9 0 0 0
Functional ≤ 10μM 47 8 2 2

Reactome Network (1)

Reactome ID Description Species
REACT_22266 Interaction between L1 and Ankyrins Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 6
SCN1B_HUMAN Q07699 CHEMBL5487 Sodium Channel Beta-1 Subunit, Human 5
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 34
SCN2B_HUMAN O60939 CHEMBL5446 Sodium Channel Beta-2 Subunit, Human 5
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 8
SCN3B_HUMAN Q9NY72 CHEMBL5488 Sodium Channel Beta-3 Subunit, Human 5
SCN4A_HUMAN P35499 CHEMBL2072 Sodium Channel Protein Type IV Alpha Subunit, Human 7
SCN7A_HUMAN Q01118 CHEMBL3585 Sodium Channel Protein Type VII Alpha Subunit, Human 11
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 5
SCN9A_HUMAN Q15858 CHEMBL4296 Sodium Channel Protein Type IX Alpha Subunit, Human 8
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 17 8 7 7

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 41
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 34
HYES_HUMAN P34913 CHEMBL2409 Epoxide Hydratase, Human 32
HYES_RAT P80299 CHEMBL5669 Epoxide Hydrolase 2, Rat 32
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 26
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 17
SCN7A_HUMAN Q01118 CHEMBL3585 Sodium Channel Protein Type VII Alpha Subunit, Human 11
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 8
SCN9A_HUMAN Q15858 CHEMBL4296 Sodium Channel Protein Type IX Alpha Subunit, Human 8
SCN4A_HUMAN P35499 CHEMBL2072 Sodium Channel Protein Type IV Alpha Subunit, Human 7
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 6
SCNAA_HUMAN Q9Y5Y9 CHEMBL5451 Sodium Channel Protein Type X Alpha Subunit, Human 6
SCNAA_RAT Q62968 CHEMBL4017 Sodium Channel Protein Type X Alpha Subunit, Rat 6
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 5
SCN1B_HUMAN Q07699 CHEMBL5487 Sodium Channel Beta-1 Subunit, Human 5
SCN2B_HUMAN O60939 CHEMBL5446 Sodium Channel Beta-2 Subunit, Human 5
SCN3B_HUMAN Q9NY72 CHEMBL5488 Sodium Channel Beta-3 Subunit, Human 5
SCN4B_HUMAN Q8IWT1 CHEMBL4689 Sodium Channel Beta-4 Subunit, Human 5
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 5
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 4
HYEP_HUMAN P07099 CHEMBL1968 Epoxide Hydrolase 1, Human 4
KCND2_RAT Q63881 CHEMBL1075227 Potassium Voltage-gated Channel Subfamily D Member 2, Rat 4
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 4
SCNAA_MOUSE Q6QIY3 CHEMBL5158 Sodium Channel Protein Type 10 Subunit Alpha, Mouse 4
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 1
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 1
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 1
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
KCNB1_RAT P15387 CHEMBL1075226 Potassium Voltage-gated Channel Subfamily B Member 1, Rat 1
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 1
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SCNBA_HUMAN Q9UI33 CHEMBL5167 Sodium Channel Protein Type XI Alpha Subunit, Human 1