UCSF

Serine/threonine-protein Kinase Sgk1, Human (27 Compounds)

Swissprot:
SGK1_HUMAN
Stitch:
SGK1_HUMAN
UniProt:
O00141
ChEMBL:
CHEMBL2343
Reactome:
REACT_160189
PDB:
2R5T (DOCK)
3HDM (DOCK)
3HDN (DOCK)
SGK1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 27 4 0 3
Binding ≤ 1μM 14 2 0 2

Reactome Network (1)

Reactome ID Description Species
REACT_160189 Stimuli-sensing channels Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
SGK1-1-E Serine/threonine-protein Kinase Sgk1 (cluster #1 Of 2), Eukaryotic 26 3 0 2
SGK1-2-E Serine/threonine-protein Kinase Sgk1 (cluster #2 Of 2), Eukaryotic 1 1 0 1
Uniprot Swissprot Chembl Description Number Shared
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 7
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 5
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 4
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 4
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 4
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 4
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 4
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 3
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 3
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 3
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 3
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 3
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 3
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 3
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 3
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 3
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 3
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 3
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 3
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 3
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 3
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 3
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 2
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 2
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 2
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 2
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 2
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 2
DYRK3_HUMAN O43781 CHEMBL4575 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 3, Human 2
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 2
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 2
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 2
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 2
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 2
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 2
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 2
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 2
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 2
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 2
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 2
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 1
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 1
IRAK1_HUMAN P51617 CHEMBL3357 Interleukin-1 Receptor-associated Kinase 1, Human 1
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 1
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 1
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 1
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 1
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 1
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 1
MAPK3_HUMAN Q16644 CHEMBL4670 MAP Kinase-activated Protein Kinase 3, Human 1
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 1
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK10_RAT P49187 CHEMBL4092 C-Jun N-terminal Kinase 3, Rat 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 1
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 1
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 1
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 1
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 1
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 1
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 1
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 1
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 1
TOPK_HUMAN Q96KB5 CHEMBL4896 PDZ-binding Kinase, Human 1
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1

Most Common Rings