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UCSF
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Analogs

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Popular Name: N-[2,6-bis(3-carbamimidoylphenoxy)-3-pyridyl]benzamide N-[2,6-bis(3-carbamimidoylphenox…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FA10-1-E Coagulation Factor X (cluster #1 Of 2), Eukaryotic Eukaryotes 120 0.28 Binding ≤ 10μM
THRB-4-E Prothrombin (cluster #4 Of 8), Eukaryotic Eukaryotes 3400 0.22 Binding ≤ 10μM
TRY1-1-E Trypsin I (cluster #1 Of 5), Eukaryotic Eukaryotes 260 0.26 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FA10_HUMAN P00742 Coagulation Factor X, Human 120 0.28 Binding ≤ 1μM
TRY1_HUMAN P07477 Trypsin I, Human 260 0.26 Binding ≤ 1μM
FA10_HUMAN P00742 Coagulation Factor X, Human 120 0.28 Binding ≤ 10μM
THRB_HUMAN P00734 Thrombin, Human 3400 0.22 Binding ≤ 10μM
TRY1_HUMAN P07477 Trypsin I, Human 260 0.26 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 5.88 -85.31 9 9 2 164 468.517 8 ↓
Lo Low (pH 4.5-6) 2.46 6.37 -150.09 10 9 3 165 469.525 8 ↓